- Diffuse Pulmonary Meningotheliomatosis: A Case Report.
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Jungsuk An, Heejung Park, Joungho Han, Tae Sung Kim, Yong Soo Choi, Moon Seok Choi, Sang Won Um
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Korean J Pathol. 2011;45:S32-S35.
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DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.S1.S32
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- Diffuse pulmonary meningotheliomatosis (DPM) is an extremely rare condition. We herein report a unique case of DPM in a 54-year-old woman with a previous history of hepatocellular carcinoma. A chest computed tomography showed diffuse bilateral nodular infiltration, suggesting miliary spread of metastatic hepatocellular carcinoma. The patient underwent a video-assisted thoracoscopic surgery for diagnostic purposes. The cut surface of the lung specimen showed multiple dispersed small nodules, consisting of variably sized nests or whorls of bland epithelioid cells often along the walls of alveolar septa or in a perivascular network within the alveolar interstitium. The tumor cells showed immunoreactivity for epithelial membrane antigen, vimentin, and progesterone receptor. DPM should be included in the differential diagnosis of diffuse multiple small nodules or a reticular pattern in the radiologic studies.
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Citations
Citations to this article as recorded by  - Minute Pulmonary Meningothelial-Like Nodules Simulating Hematogenous Lung Metastasis: A Case Report
Sang Kook Lee, Gi Jeong Kim, Young Jae Kim, Ah Young Leem, Eu Dong Hwang, Se Kyu Kim, Joon Chang, Young Ae Kang, Song Yee Kim
Tuberculosis and Respiratory Diseases.2013; 75(2): 67. CrossRef
- Thymofibrolipoma: A Brief Case Report.
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Gu Hyun Kang, Joungho Han, Tae Sung Kim, Yong Soo Choi, Sang Won Um
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Korean J Pathol. 2010;44(3):338-340.
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DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.3.338
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2,775
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- Thymofibrolipoma is an extremely rare tumor in the anterior mediastinum, and represents a histologic variant of the usual thymolipoma. Herein, we report a case of thymofibrolipoma in a 9-year-old girl who had a huge mass with fatty attenuation in the right hemithorax on chest computed tomography. She denied any subjective symptoms except mild fever. The surgically resected tumor was ovoid, soft and well-encapsulated, measuring 9.0 x 7.5 x 7.0 cm.
The cut surface was light tan in color with yellowish streaks. Microscopically, two distinct areas were admixed in different proportions. One consisted of normal thymic tissue with subinvoluted features and the other was composed of extensive areas of collagenous tissue interspersed in mature adipose tissue. In a high power view, there were thin strands of remnant thymic epithelial cells, separating the pseudolobules. Thymofibrolipoma should be distinguished from other benign or malignant conditions, occurring in the anterior mediastinum, so that unnecessary treatment can be avoided.
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Citations
Citations to this article as recorded by - Unusual thymoma subtypes
Michael A. den Bakker
Diagnostic Histopathology.2023; 29(2): 105. CrossRef - Thymofibrolipoma: a case report and review of the literature
Ryu Jokoji, Emiko Tomita
Diagnostic Pathology.2022;[Epub] CrossRef - Thymoangiolipoma: A rare histologic variant of thymolipoma in a patient with myasthenia gravis
Mohammad Hossein Anbardar, Fatemeh Amirmoezi, Armin Amirian
Rare Tumors.2020; 12: 203636132097921. CrossRef
- Squamous Cell Carcinoma Arising in a Thymic Cyst : A Brief Case Report.
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Chang Ohk Sung, Joungho Han, Ji Yeon Kim, Young Mog Shim, Tae Sung Kim
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Korean J Pathol. 2009;43(3):260-262.
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DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.3.260
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3,188
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- We present here the case of a 73-year-old man with squamous cell carcinoma that arose in a thymic cyst, and this was incidentally found by chest radiography. Computed tomography revealed a 3.6 cm-sized predominantly cystic lesion with a mural nodule at the antero-superior mediastinum. The resected specimen was a well demarcated cystic mass with a solid mural nodule. Microscopically, the nodule was determined to be invasive squamous cell carcinoma that had originated from the benign squamous epithelium lining the thymic cyst.
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Citations
Citations to this article as recorded by - Multilocular Thymic Cyst with Prominent Lymphoid Follicular Hyperplasia: A Case Report
Na-Ra Yoon, Ji Yun Jeong, Joungho Han, Jhingook Kim, Chin A Yi
Journal of Lung Cancer.2012; 11(1): 45. CrossRef
- Mucous Gland Adenoma Presenting as a Peripheral Lung Mass: A Brief Case Report.
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Ji Eun Kwon, Gou Young Kim, Joungho Han, Tae Sung Kim, Kwanmien Kim
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Korean J Pathol. 2004;38(2):126-128.
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- Mucous gland adenoma (MGA) of the lung is an uncommon, benign tumor that histologically resembles the mucus-secreting component of the tracheobronchial gland. The majority arises within the main, lobar or segmental bronchi.
MGA presenting as a peripheral lung mass is extremely rare.
We herein report a case of MGA that uniquely arose from the peripheral territory of the superior segmental bronchus of the left lower lobe in a 73-year-old male. Chest computed tomography showed a 13 mm-sized, subpleural nodule, which was easily enucleated by video-assisted thoracotomy. The mass was round and gray-tan in color with mucoid material.
The tumor was composed of cysts, tubules, and glands lined by bland columnar, cuboidal or flattened, mucus secreting cells.
- Primary Signet Ring Cell Carcinoma with Widespreand Metastasis.
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Nam Hoon Cho, Soon Hee Jung, Tae Sung Kim
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Korean J Pathol. 1988;22(4):448-455.
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- We present an autopsy case of signet ring cell carcinoma of urinary bladder which underwent widespread metastsis through nearly entire organ. The patient, 45-year old male, suffered from hematuria, dysuria and flank pain for 6 months. Under the diagnosis of the signet ring cell carcinoma by the cystoscopic biopsy, radical cystectomy and ileocutaneous ureteral division were performed. But he died after 11-months after the diagnosis. The autopsy confirmed the widespread metastasis at the lung, kidney, adrenal gland, parathyroid gland, heart, stomach, ileum, spine, rib and meninges. The preveously resected urinary bladder discolosed the well defined fungating mass at the dome and anterio-lateral portion without apparent evidence of the remnant of the urachus. Histologically, the signet ring cells were predominent and focally mucinous pool floating the signet ring cells was noted. We could find several foci of the well differentiated adenocarcinoma and poorly differentiated adenocarcinomas. The above findings may reflect that the origin of carcinoma may be from the multipotential transitional cell epithelium.
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